ibs-smart™ is a blood test that detects validated 

IBS biomarkers.

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A 2,300+ patient study conducted at Cedars Sinai validated anti-CdtB and anti-vinculin as highly specific biomarkers for IBS.  




If either antibody biomarker is 'Elevated,' your test results can be considered 'Positive.'

If your ibs-smart™ results are positive:

Get a confident IBS diagnosis. 

Instead of simply ruling out other diseases, let positive results from a blood test provide you with a confident IBS diagnosis that is based on organic biomarkers. 

Know the cause.

If the measured biomarkers are elevated, IBS developed from gastroenteritis (food poisoning). Here's how food poisoning leads to IBS.

Potentially avoid invasive testing.

If your doctor determines you have no other alarm symptoms, further testing may be unnecessary. 

Download the ibs-smart™

Results Interpretation Guide

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The validation study for ibs-smart™ showed that elevated biomarkers indicated IBS with up to 98% certainty. This test is highly specific in distinguishing between IBS and IBD. 

Is ibs-smart™ right for YOU?

Do you have IBS symptoms,

including diarrhea? 

​These include: 

  • Abdominal pain and cramping

  • Chronic bloating

  • Chronic diarrhea, or

  • Alternating diarrhea and constipation

If you do, ibs-smart™ could finally give you answers about your symptoms and their cause. 

IBS can occur alongside other serious illnesses. Ensure that you have thoroughly discussed all of your symptoms with your doctor to determine whether additional testing is necessary. 


If you suffer from IBS symptoms, you’re not alone. In fact, 40 million Americans and 15% of the world population suffer along with you. 

ibs-smart™ costs $220 with your doctor, 

or $199 through our online service.

ibs-smart™ is covered at least in part by many common insurance plans. 

The patient responsibility for Medicare and Medicaid patients is $0.

The CPT code is 83520 and is billed twice ($110 once for each antibody). 

ibs-smart™ could help you avoid potentially unnecessary invasive procedures.  

A published cost minimization model showed an IBS blood test could save up to $800 per patient by preventing unnecessary procedures like colonoscopies.  

Read the study here. 


Ready to get ibs-smart™?

ibs-smart™ is a doctor-ordered test. 


Remote Prescriber

we'll connect you with a doctor.


Your doctor

Work with your doctor

Canadian patient? Click here


ibs-smart™️ is brought to patients by Gemelli Biotech. 

Learn more about our work, principles and leadership at www.gemellibiotech.com.

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ibs-smart™️ is the only licensed, patented antibody blood test for the diagnosis of IBS. See the full list of patents here

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