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How to Diagnose IBS with Our

With our telehealth provider service, you can order ibs-smart™ online by answering a few questions about your symptoms. 

Once completed, your symptom screening will be evaluated by a qualified telehealth provider. If ibs-smart™ is right for you, a signed test order form will be emailed to you within 48 hours.

Once your blood sample has been received and tested, you will have the option for a free phone consultation with your telehealth provider to discuss your results.


Not in the US? Click here.





Complete the symptoms screening questionnaire & order your ibs-smart™ collection kit to be shipped to your home.



Once ibs-smart™ is ordered by your telehealth provider, a signed test order form will be emailed to you. Please print and include this with your ibs-smart™ collection kit when it arrives.



You can bring your kit to any blood draw lab to collect & ship your blood sample. Prepaid shipping materials included.


Find an independent blood draw lab close to you.

What's in the kit? 

The kit contains professional blood draw materials and prepaid return shipping



Your ibs-smart™ test results will be emailed directly to you. You will also receive instructions to schedule a free phone consultation with your telehealth provider. 


As part of this consultation, your provider won't be able to prescribe treatment or diagnose other illnesses, but he or she will ensure you have a clear understanding of your ibs-smart™ results.


When ordering ibs-smart™ through the telehealth prescriber service, ibs-smart™ is $199. If it is determined that the test is not right for you, you will be refunded the full cost of the test.

Along with your results, you will receive an itemized bill for use when filing an insurance claim. ibs-smart™ is covered at least in part by many common insurance plans. 

If you're interested in asking your insurance provider about coverage, you can reference procedure code: 83520, which is billed twice (once for each antibody). 

Medicare does not cover telehealth services. If you would like to use your Medicare coverage for ibs-smart™, please click here.


Enter patient information below to get started. 


THE STORY OF ibs-smart™

  • For decades, it was believed that IBS was caused by physiological factors like anxiety.

  • In 2015, a 2,300-patient study on the progression of food poisoning to IBS led to the discovery of two biomarkers, anti-CdtB and anti-vinculin, that indicate IBS.

  • ibs-smart™ was developed to measure these biomarkers and confidently diagnose IBS so patients can quickly begin a personalized treatment plan.

Commonly Asked Questions

for Diagnosing IBS

How is IBS diagnosed?

Recently, scientists have identified biomarkers for IBS (anti-CdtB and anti-vinculin) that are measurable in a patient's blood. While these biomarkers do not indicate all forms of IBS, they are effective in diagnosing the majority of IBS-D (diarrhea-predominant) and IBS-M (diarrhea and constipation mixed) cases. ibs-smart™ is the only licensed and patented blood test for the diagnosis of IBS.


In the past, IBS has traditionally been diagnosed by multiple tests to exclude the possibility of other diseases. If, through this process, no other health issues are found, a diagnosis of IBS is made. Additional testing can include colonoscopy, endoscopy, stool test, radiography, celiac panel, and a GI breath test.

Which types of IBS does ibs-smart™ help diagnose?

ibs-smart™ is useful in the diagnosis of IBS-D  (diarrhea-predominant)  and IBS-M  (diarrhea and constipation mixed). 


However, ibs-smart™ is not useful in the diagnosis of IBS-C (constipation-predominant), because the antibodies that the test measures are not often found to be elevated in patients with IBS-C. 

How accurate is an ibs-smart™ diagnosis?

ibs-smart™ is the only licensed and patented antibody blood test for IBS and is a second-generation test for the measurement of anti-CdtB and anti-vinculin. (citation


ibs-smart™ has been scientifically validated and is performed in a CLIA-certified laboratory. 


Patients with elevated levels of either anti-CdtB or anti-vinculin, as measured by ibs-smart™, can be diagnosed with IBS with 96% certainty (positive predictive value).


Patients with elevated levels of both anti-CdtB and anti-vinculin antibodies, as measured by ibs-smart™, can be diagnosed with IBS with 100% certainty (positive predictive value). 

Not in the US? You can still diagnose IBS with ibs-smart™.

ibs-smart™ is available in several countries and territories through partnerships with the labs listed here: 




Please contact the lab directly to inquire about ordering ibs-smart™. We are actively expanding our partnerships. If you would like to stay in touch about the availability of ibs-smart™ in your country, please contact us

Man found out he didn't have ibs from ib



ibs-smart™️ is the only licensed, patented antibody blood test for the diagnosis of IBS. See the full list of patents here

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ibs-smart™️ is brought to patients by Gemelli Biotech. 

Learn more about our work, principles and leadership at www.gemellibiotech.com.

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