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IBS Diagnostics
With Dr. Mark Pimentel


What Is ibs-smart and How Does It Diagnose IBS?

 How Food Poisoning Leads to IBS


Biomarker and Blood Test Validation


Clinical Applications of
ibs-smart for Gastroenterologists


Clinical Applications of ibs-smart for Primary Care Physicians


Selecting Patients and Patient Counseling


 Understanding the Test Results


Recommendations for Patients With Positive Test Results



Dr. Mark Pimentel In Lab Coat

Mark Pimentel, MD, is Professor of Medicine at Geffen School of Medicine and Cedars-Sinai Medical Center in Los Angeles, California.


Active in research, Dr. Pimentel has served as a principal investigator or co-investigator for numerous basic science, translational and clinical studies in such areas as IBS and the relationship between gut flora composition and human disease. 



A few of Dr. Pimentel’s most significant accomplishments include:


  1. Discovered rifaximin as a treatment for irritable bowel syndrome (IBS). 

  2. Developed the first blood test for IBS on the basis of IBS being derived from acute gastroenteritis. 

  3. Described the association between IBS and bacterial overgrowth which forms the basis for microbiome therapies in this condition. 

  4. Uncovered the methanogen (Methanobrevibacter smithii) as an agent for causing constipation in humans. 

  5. Discovered the use of lovastatin as a microbiome treatment for constipation on the basis of inhibiting methane production by methanogens.