Doctor Crop 2 Purple.jpg

Results 
Interpretation

ibs-smart-whiteBG-cmyk-WIX.png

IBS Blood Test Results

Results_Explainer_V003.png

If either antibody is "Elevated," the test results can be considered positive and the patient can be confidently diagnosed with IBS-D or IBS-M.

If both antibodies are "Not Elevated," the test results can be considered non-indicative of post-infectious IBS. Further testing may be required in this case.

ibs-smart is a Laboratory Developed Test, conducted at a CLIA-Certified Partner. PacificDx

ibs-smart Results Interpretation Guide

Screen Shot 2021-04-13 at 12.51.48 PM.pn

Anti-CdtB: Elevated | Anti-Vinculin: Not Elevated

Positive for Irritable Bowel Syndrome (IBS)

Specificity 94% | Positive Predictive Value 96%

Understanding the Results: Anti-CdtB Elevated, Anti-vinculin Not Elevated
Play Video
  • Suggests recent or past gastroenteritis. 

  • Immune system has responded to CdtB toxin with antibodies.  

  • Studies show that anti-CdtB predicts a disturbed microbiome has occurred after gastroenteritis. 

  • The patient is at higher risk for subsequent infectious enteritis.

 
 

Anti-CdtB: Not Elevated | Anti-Vinculin: Elevated

Positive for Irritable Bowel Syndrome (IBS)

Specificity 91% | Positive Predictive Value 96%

  • Initial gastroenteritis may have occurred a long time ago. 

  • Anti-vinculin, an autoimmune response, has developed and an altered microbiome may be seen. 

  • Elevated anti-vinculin levels may indicate a more severe condition and a greater chronicity of disease. (Anti-vinculin autoimmunity usually develops 3-4 months after the infection.)

  • The patient is at higher risk for subsequent infectious enteritis.