ibs-smart™ measures biomarkers in your blood that indicate IBS with 96% - 100% certainty.

ibs-smart™ is applicable to patients with diarrheal symptoms and diagnoses diarrhea-predominant or mixed-type IBS (IBS-D or IBS-M). 

These biomarkers are not common in patients with constipation-predominant IBS (IBS-C). 




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The validation study for ibs-smart™ showed that elevated biomarkers indicated IBS with up to 100% certainty. This test is highly specific in distinguishing between IBS and IBD. 

Is ibs-smart™ right for YOU?

Have you been experiencing the following for a few weeks or more? 

  • Abdominal pain and cramping

  • Chronic bloating

  • Chronic diarrhea

  • Alternating diarrhea and constipation

If you have, ibs-smart™ could help you begin appropriate treatment quickly and prevent years of potentially unnecessary procedures like colonoscopies.

IBS can occur alongside other serious illnesses. Ensure that you have thoroughly discussed all of your symptoms with your doctor to determine whether additional testing is necessary. 

If either antibody biomarker is 'Elevated,' your test results can be considered 'Positive.'

If your ibs-smart™ results are positive:

Download the ibs-smart™

Results Interpretation Guide

You know with certainty that you have IBS.

The organic biomarkers tested by ibs-smart™ have a positive predictive value of IBS that is 96%-100%. 

You know the cause,

which may inform treatment.

If the measured biomarkers are elevated, your IBS developed from gastroenteritis (food poisoning). This means your gut microbiome has been disrupted, indicating that treatments that target the gut microbiome could be effective for you. 

Here's how food poisoning leads to IBS.

You could avoid years of additional testing and costs

If your doctor determines you have no other alarm symptoms, further testing may be unnecessary. 

ibs-smart™ is covered at least in part by many common insurance plans. 

The patient responsibility for Medicare and Medicaid patients is $0.

The CPT code is 83520 and is billed twice ($110 once for each antibody). 

The uncovered cost of ibs-smart™ is $220.

Studies show the test could save you over $800 by helping you avoid potentially unnecessary procedures.

Ready to get ibs-smart™?

ibs-smart™ is a doctor-ordered test. 


Have an online prescriber evaluate your symptoms and order ibs-smart™ if it's right for you.


Or work with your current doctor to order ibs-smart™.


ibs-smart™️ is brought to patients by Gemelli Biotech. 

Learn more about our work, principles and leadership at www.gemellibiotech.com.

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ibs-smart™️ is the only licensed, patented antibody blood test for the diagnosis of IBS. See the full list of patents here

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